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Sorted by category: Clinical Trials | View All
September 16, 2015

Do Clinical Trials Work?

Clinical trials are a critical part of getting a drug approved by the FDA - but since they often come under fire due to their low success rates, it's time to take a new direction.

June 14, 2015

On The Horizon

Developments in ALS/MND research move at a swift pace, from skin providing diagnostic tissue to stem cell clinical trials about to receive FDA approval.   

March 16, 2015

Why Upper Motor Neurons Degenerate in ALS

Hande Ozdinler, Ph.D. at Northwestern University, has presented a new paper that supports and advances earlier studies that suggest ALS begins in the brain rather than the spinal cord.

January 29, 2015

A Review of Closed Clinical Trials

While there have been many clinical trials for ALS over the past 10 to 15 years, the results have frequesntly been unsuccessful.  A brief rationale is offered for your review. 

January 29, 2015

Restructuring Clinical Trial Design

Dexpramipexole, once thought to be the light at the end of a very dark tunnel, fell victim to the 'valley of death' Phase III clinical trial in 2013.

January 29, 2015

Why Most Clinical Trials Fail

Many scientists feel that today there exist better, more relevant testing models than SOD1 mice. There are far better models now available for testing new pharmaceuticals.